Increased Circulating Chemerin in Relation to Chronic Microvascular Complications in Patients with Type 2 Diabetes
Table 5
Clinical characteristics of type 2 diabetic subjects according to the presence and severity of diabetic retinopathy.
No DR
NPDR
PDR
p
Number (n)
131
68
26
Age (years)
53.91 (12.21)
53.95(12.44)
53.61(11.80)
NS
Sex (male/female)
90/41
38/30
15/11
NS
Duration of diabetes (years)△
2(0.8,9)
7(3,13)∗
8.0(3,14.0)∗
<0.001
Waist circumference(cm)
86.63 (11.12)
87.17(11.09)
87.23(8.43)
NS
BMI (kg/m2)
24.91(3.46)
24.89(2.95)
26.06(4.61)
NS
SBP (mmHg)
125.01(13.26)
128.83(15.53)
121.11(9.08)
NS
DBP (mmHg)
78.37(7.47)
79.70(5.93)
78.30(4.18)
NS
Glycated hemoglobin (%)
8.03(1.45)
8.78(2.24)∗
9.24(2.46)∗
0.001
Triglycerides (mmol/l) △
1.62(1.15,2.21)
1.58(1.06,2.40)
1.77(1.14,2.86)
NS
Total cholesterol (mmol/l)
4.62(1.03)
5.07(1.07)∗
4.81(1.04)
0.017
HDL cholesterol (mmol/l)△
1.07(0.30)
1.13(0.27)
1.11(0.27)
NS
LDL cholesterol (mmol/l)
2.77(0.75)
2.96(0.86)
2.88(0.87)
NS
Serum Creatinine (umol/l)
55.53(13.58)
51.25(14.69)∗
48.19(10.10)∗
0.02
UAE (mg/24h)△
13.2(9,17.0)
13.8(10.80,19.0)
15.0(8.9,19.1)
NS
hs-CRP (mg/L) △
3.6(1.2,6.6)
6.9(2.62,11.0)
3.80(0.92,8.45)
NS
Chemerin (ng/ml)
97.69(40.27)
112.66(38.34)∗
119.95(48.62)∗
0.007
Medication
0.015
Oral hypoglycemic agents
33(25.1%)
22(32.35%)
4(15.38%)
Insulin
98(74.9%)
46(67.65%)
22(84.62%)
Hypertension (%)
71(54.19%)
42(61.70%)
17(65.38%)
NS
Numerical variables are expressed as the mean with SD and median (interquartile range). Categorical variables were presented as number (percentage). P-value for difference between the groups was calculated from the analysis of a one-way ANOVA and ∗vs. No DR. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; Scr, serum creatinine; UAE, urinary albumin excretion; hs-CRP, high sensitivity C-reactive protein; NS, not significant. △Natural logarithmic transformation was used in analysis.
