GNPDA2 Gene Affects Adipogenesis and Alters the Transcriptome Profile of Human Adipose-Derived Mesenchymal Stem Cells

Figure 2

Filtering of probe sets to identify differentially expressed genes in OEG, V1, InG, and V2. We investigated the transcriptome changes with Affymetrix HTA 2.0 microarrays containing 70753 probe sets. If they showed t test value <0.05 and a fold change <−2.0 or >2.0, the genes were considered differentially expressed. 107 and 599 probe sets were filtered with these criteria in OEG compared with V1 and InG compared with V2, respectively. The table is giving the numbers of upregulated or downregulated and coding or noncoding transcripts. OEG: GNPDA2 overexpressed ADMSCs; V1: the control cells of OEG; InG: GNPDA2 shRNA knockdown ADMSCs; V2: the control cells of InG. (a) OEG vs. V1. (b) InG vs. V2.

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