Low Frequency of MKRN3 and DLK1 Variants in Chinese Children with Central Precocious Puberty

Figure 4

Native structure of the produced MKRN3 protein using ab initio modeling. The three C3H1 zinc-finger motifs are shown in yellow, the C3HC4 RING finger motif is in green, and the MKRN-specific Cys-His domain is shown in purple. The four missense variant residues are highlighted with red spheres.