High-Normal Preconception TSH Levels Have No Adverse Effects on Reproductive Outcomes in Infertile Women Undergoing the First Single Fresh D5 Blastocyst Transfer

Table 3

The impact of preconception high-normal TSH levels on clinical outcomes.

	Clinical pregnancy		Miscarriage		Live birth
	aOR (95% CI)		aOR (95% CI)		aOR (95% CI)
TSH (low vs. high-normal level)	0.84 (0.63–1.12)^a	0.234	0.65 (0.37–1.16)^a	0.145	0.61 (0.34–1.05)^a	0.083
Age (years)	0.99 (0.96–1.04)	0.941	0.92 (0.85–0.98)^b	0.015	1.10 (1.03–1.19)^b	0.005
AMH (pmol/L)	1.01 (1.00–1.09)^c	0.049	1.01 (0.99–1.02)	0.448	0.99 (0.98–1.01)	0.441
Quality of blastocyst	1.61 (1.16–2.23)^d	0.006	1.02 (0.52–2.02)	0.949	1.39 (0.75–2.59)	0.341
Causes of infertility	0.90 (0.76–1.07)	0.223	0.87 (0.63–1.22)	0.421	0.86 (0.62–1.19)	0.865

^aHigh-normal TSH levels had no impact on clinical pregnancy, miscarriage, or live birth. ^bYounger age predicted lower odds of miscarriage and higher odds of live birth. ^cHigher serum AMH predicted very slightly higher odds of clinical pregnancy. ^dTop quality blastocysts predicted higher odds of clinical pregnancy.