The Genetic Perspective of Familial Glucocorticoid Deficiency: In Silico Analysis of Two Novel Variants

Figure 2

(a) Substitution of p.Ile84Asn in the MC2R gene: the left panel is the wild type, and the right panel is mutant asparagine. The interaction of the amino acids was changed in the substitutions. (b) Substitution of p.Leu43Arg in the MC2R gene and amino acid interaction change. Characterization of the reported MC2R and MRAP variants.

(a)

(b)