International Journal of Endocrinology

Research Article

Associations of Triglyceride-Glucose Index and Its Derivatives with Hyperuricemia Risk: A Cohort Study in Chinese General Population

Table 1

Baseline characteristics of subjects grouped according to the tertiles of TyG.


Variable	Total	TyG			value
Variable	Total	T1 (<8.24)	T2 (8.24–8.75)	T3 (<8.75)	value

No., n	42,387	14129	14127	14131	—
Women (%)	43.7	63.7	42.5	24.8	<0.001
Age, y	43.1 ± 12.3	38.4 ± 11.2	43.4 ± 12.3	47.4 ± 11.7	<0.001
SBP (mmHg)	121.2 ± 16.7	115.4 ± 14.9	121.0 ± 16.2	127.2 ± 16.8	<0.001
DBP (mmHg)	73.6 ± 11.3	69.4 ± 10.1	73.4 ± 10.9	77.9 ± 11.2	<0.001
HR (bmp)	79.9 ± 12.2	80.2 ± 12.4	79.6 ± 12.2	79.9 ± 12.0	<0.001
BMI (kg/m²)	23.2 ± 3.1	21.6 ± 2.6	23.1 ± 2.9	24.8 ± 2.9	<0.001
WC (cm)	78.4 ± 9.7	72.7 ± 7.9	78.2 ± 8.9	84.3 ± 8.7	<0.001
WHR	0.84 ± 0.07	0.80 ± 0.06	0.84 ± 0.06	0.88 ± 0.06	<0.001
WHtR	0.47 ± 0.05	0.44 ± 0.04	0.47 ± 0.05	0.50 ± 0.05	<0.001
Urate (μmol/L)	318.9 ± 61.6	292.6 ± 60.0	318.9 ± 59.3	345.3 ± 53.5	<0.001
FPG (mmol/L)	5.56 ± 1.13	5.15 ± 0.46	5.42 ± 0.59	6.11 ± 1.66	<0.001
TC (mmol/L)	4.76 ± 0.88	4.42 ± 0.77	4.75 ± 0.81	5.12 ± 0.93	<0.001
TG (mmol/L)	1.42 ± 1.18	0.70 ± 0.15	1.15 ± 0.19	2.41 ± 1.59	<0.001
HDLc (mmol/L)	1.56 ± 0.36	1.74 ± 0.34	1.58 ± 0.33	1.40 ± 0.32	<0.001
LDLc (mmol/L)	2.50 ± 0.77	2.29 ± 0.62	2.56 ± 0.68	2.61 ± 0.91	<0.001
eGFR (mL/min/1.73 m²)	79.4 ± 20.3	83.1 ± 18.9	80.6 ± 21.1	78.2 ± 19.8	<0.001
TyG	8.55 ± 0.62	7.93 ± 0.24	8.49 ± 0.14	9.24 ± 0.46	<0.001
TyG-BMI	198.9 ± 35.9	171.2 ± 22.0	196.0 ± 25.6	229.6 ± 31.6	<0.001
TyG-WC	673.4 ± 116.5	577.1 ± 68.7	664.2 ± 78.1	779.0 ± 97.0	<0.001
TyG-WHtR	4.06 ± 0.65	3.51 ± 0.38	4.00 ± 0.43	4.65 ± 0.55	<0.001

T, tertile; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; BMI, body mass index; WC, waist circumference; WHR, waist-to-hip ratio; WHtR, waist height ratio; FPG, fasting plasma glucose; TC, total cholesterol; TG, triglyceride; HDLc, high-density lipoprotein cholesterol; LDLc, low-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; TG, triglyceride; the asterisk means value for the difference of variables between T1 and T3.