Mitochondrial DNA: A New Predictor of Diabetic Kidney Disease

Table 1

Clinical trial about mtDNA changes in DKD or T2DM.

Author	Year	Samples (n)	Treatment group	Control group	Observation index	value
Sharma et al. [13]	2013	32	DKD	Healthy	Urinary mtDNA	≤0.01
Deng et al. [22]	2019	244	T2DM	Healthy	Plasma mtDNA	<0.001
Al-Kafaji et al. [23]	2018	100	DKD	T2DN	Plasma mtDNA	<0.01
Al-Kafaji et al. [23]	2018	100	DKD	Healthy	Plasma mtDNA	<0.01
Cao et al. [24]	2018	77	DKD	Healthy	Plasma mtDNA	0.012
Cao et al. [24]	2018	77	DKD	Healthy	Urinary mtDNA/Cr ratio	<0.001
Jiang et al. [25]	2019	108	DKD	T2DM	Plasma mtDNA	0.036