The Effect of Iodine Status on the Risk of Thyroid Nodules: A Cross-Sectional Study in Zhejiang, China
Table 3
Effect of urinary iodine concentration on thyroid nodule according to the iodine nutritional status evaluation criteria of the WHO.
Group
UIC (μg l−1)
Model 1a
Model 2b
Model 3c
Model 4d
OR (95% CI)
OR (95% CI)
OR (95% CI)
OR (95% CI)
All
<100
1.00
1.00
1.00
1.00
100–199
0.75 (0.58–0.97)
0.03
0.75 (0.58–0.97)
0.03
0.78 (0.61–1.01)
0.06
0.79 (0.61–1.03)
0.08
200–299
0.54 (0.39–0.75)
0.00
0.54 (0.39–0.75)
0.00
0.62 (0.44–0.87)
0.01
0.62 (0.45–0.87)
0.01
300–399
0.43 (0.24–0.76)
0.00
0.43 (0.24–0.76)
0.00
0.52 (0.29–0.92)
0.03
0.53 (0.30–0.94)
0.03
400–499
0.42 (0.18–1.00)
0.05
0.42 (0.18–1.00)
0.05
0.52 (0.21–1.25)
0.14
0.52 (0.22–1.26)
0.15
≥500
0.73 (0.39–1.36)
0.32
0.73 (0.39–1.37)
0.33
0.85 (0.45–1.60)
0.61
0.88 (0.47–1.67)
0.71
Male
<100
100–199
0.83 (0.56–1.23)
0.34
0.82 (0.55–1.22)
0.33
0.84 (0.56–1.25)
0.39
0.84 (0.56–1.25)
0.39
200–299
0.55 (0.34–0.91)
0.02
0.55 (0.34–0.91)
0.02
0.63 (0.38–1.04)
0.07
0.63 (0.38–1.05)
0.07
300–399
0.57 (0.26–1.26)
0.16
0.57 (0.26–1.26)
0.17
0.74 (0.33–1.65)
0.46
0.74 (0.33–1.66)
0.47
400–499
0.31 (0.07–1.34)
0.12
0.31 (0.07–1.36)
0.12
0.39 (0.09–1.74)
0.22
0.39 (0.09–1.73)
0.22
≥500
1.29 (0.55–3.01)
0.56
1.31 (0.56–3.05)
0.53
1.48 (0.63–3.48)
0.37
1.50 (0.64–3.54)
0.35
Female
<100
100–199
0.71 (0.51–0.98)
0.04
0.71 (0.51–0.98)
0.04
0.75 (0.54–1.05)
0.09
0.77 (0.55–1.07)
0.12
200–299
0.54 (0.35–0.83)
0.01
0.54 (0.35–0.84)
0.01
0.62 (0.40–0.97)
0.04
0.63 (0.40–0.98)
0.04
300–399
0.33 (0.15–0.76)
0.01
0.34 (0.15–0.76)
0.01
0.38 (0.16–0.86)
0.02
0.39 (0.17–0.89)
0.03
400–499
0.52 (0.18–1.54)
0.24
0.52 (0.17–1.54)
0.24
0.63 (0.21–1.88)
0.40
0.63 (0.21–1.90)
0.41
≥500
0.42 (0.16–1.10)
0.08
0.42 (0.16–1.11)
0.08
0.50 (0.19–1.32)
0.16
0.53 (0.20–1.39)
0.20
aAdjusted for gender, age (continuous variable), education, and profession.bAdditionally adjusted for hypertension.cAdditionally adjusted for BMI, waist circumference, FBG, OTGG-2h, HbA1c, TC, LDL-C, and UA.dAdditionally adjusted for TSH and TGAb.
