Research Article

Quality of Life in Patients with Acromegaly before and after Transsphenoidal Surgical Resection

Table 1

Quality of life before and after operation in acromegalic patients.

Baseline (%)3-month follow-up (%)6-month follow-up (%) for repeated measure

SF-3665.3 (63.2–69.2)66.1 (64.9–72.8)75.3 (63.9–83.2)≤0.001
Physical functioning90.0 (90.0–95.0)85.0 (85.0–95.0)90.0 (80.0–100.0)0.001
Role physical50.0 (25.0–75.0)25.0 (25.0–75.0)75.0 (75.0–100.0)≤0.001
Bodily pain74.0 (74.0–80.0)84.0 (74.0–100.0)72.0 (70.0–84.0)≤0.001
General health45.0 (27.0–57.0)75.0 (52.0–82.0)67.0 (50.0–77.0)≤0.001
Vitality70.0 (50.0–75.0)45.0 (40.0–70.0)65.0 (55.0–75.0)0.669
Role emotional33.3 (0.0–100.0)66.7 (66.7–100.0)100.0 (66.7–100.0)≤0.001
Social functioning100.0 (100.0–100.0)87.5 (62.5–100.0)100.0 (100.0–100.0)0.894
Mental health72.0 (52.0–72.0)56.0 (56.0–68.0)68.0 (56.0–80.0)0.170
Health transition50.0 (25.0–50.0)50.0 (50.0–75.0)75.0 (50.0–75.0)≤0.001
AcroQoL59.1 (51.8–71.8)74.5 (70.0–76.4)77.3 (59.1–87.5)≤0.001
Appearance57.1 (48.6–62.9)54.3 (54.3–60.0)62.9 (54.3–82.9)≤0.001
Personal relation74.3 (62.9–80.0)91.4 (77.1–91.4)82.9 (65.7–91.4)≤0.001
Physical65.0 (47.5–77.5)77.5 (72.5–82.5)82.5 (62.5–90.0)≤0.001