The Prevalence of Single and Multiple Thyroid Nodules and Its Association with Metabolic Diseases in Chinese: A Cross-Sectional Study

Table 3

Association between metabolic diseases and thyroid nodules analyzed by univariable logistic regression (N = 9146).

	Factors	β	SE	Walds	value	OR	95% CI
Total	Female	0.81	0.05	283.08	<0.01	2.25	2.05–2.47
	Age
	18–40				1.0	1.0 (ref)
	41–50	0.55	0.06	75.32	<0.01	1.73	1.53–1.95
	51–60	0.94	0.07	187.11	<0.01	2.56	2.24–2.93
	61–70	1.39	0.10	193.59	<0.01	4.00	3.29–4.86
	>70	2.16	0.25	74.53	<0.01	8.67	5.31–14.16
	High TG	0.01	0.05	0.03	0.87	1.01	0.91–1.12
	Normal blood sugar				1.0	1.0 (ref)
	IGR	0.07	0.06	1.48	0.22	1.07	0.96–1.19
	DM	0.21	0.07	10.14	<0.01	1.24	1.09–1.41
	HUA	0.05	0.05	0.90	0.34	1.05	0.95–1.17
Male	Age
	18–40				1.0	1.0 (ref)
	41–50	0.51	0.08	42.19	<0.01	1.67	1.43–1.95
	51–60	0.88	0.08	103.13	<0.01	2.42	2.04–2.87
	61–70	1.45	0.13	130.44	<0.01	4.28	3.33–5.49
	>70	2.38	0.34	48.23	<0.01	10.77	5.51–21.07
	Central obesity	0.17	0.06	8.21	<0.01	1.19	1.06–1.34
	Normal blood sugar				1.0	1.0 (ref)
	IGR	0.01	0.07	0.04	0.85	1.01	0.88–1.16
	DM	0.19	0.08	5.40	0.02	1.21	1.03–1.42
	MS	-0.06	0.08	0.52	0.47	0.94	0.81–1.10
Female	Age
	18–40				1.0	1.0 (ref)
	41–50	0.60	0.10	33.79	<0.01	1.82	1.49–2.23
	51–60	1.03	0.11	86.10	<0.01	2.81	2.26–3.50
	61–70	1.33	0.16	71.87	<0.01	3.77	2.78–5.13
	>70	1.99	0.36	30.98	<0.01	7.33	3.63–14.77
	BMI
	18.5∼23.99				1.0	1.0 (ref)
	24∼7.9	0.08	0.10	0.66	0.42	1.08	0.90–1.30
	≥28	0.06	0.16	0.15	0.70	1.06	0.78–1.46
	Hypertension	−0.01	0.10	0.02	0.90	0.99	0.81–1.21
	Central obesity	−0.04	0.10	0.12	0.73	0.97	0.79–1.18
	High TG	−0.14	0.10	1.92	0.17	0.87	0.71–1.06
	High TC	0.01	0.11	0.01	0.94	1.01	0.81–1.26
	High LDL-C	−0.01	0.12	0.01	0.91	0.99	0.78–1.25
	Normal blood sugar				1.0	1.0 (ref)
	IGR	0.02	0.09	0.05	0.82	1.02	0.85–1.23
	DM	0.01	0.13	0.01	0.95	1.01	0.78–1.31
	HUA	0.09	0.11	0.70	0.40	1.09	0.89–1.35
	MS	0.17	0.11	2.61	0.11	1.19	0.96–1.47
	Fatty liver	0.29	0.09	9.54	<0.01	1.34	1.11–1.60

Note: TG: triglyceride; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; IGR: sugar adjustment; DM: diabetes mellitus; BMI: body mass index; HUA: hyperuricemia; MS: metabolic syndrome.