Relationship between Serum Indirect Bilirubin Level and Insulin Sensitivity: Results from Two Independent Cohorts of Obese Patients with Impaired Glucose Regulation and Type 2 Diabetes Mellitus in China

Table 6

Correlations between the postoperative percentage change in serum bilirubin levels (∆TBIL%, ∆DBIL%, and ∆IBIL%) and the changes of metabolism variables in cohort 2.

	∆TBIL%		∆DBIL%		∆IBIL%
	r	value	r	value	r	value
∆BMI (kg/m^2)	−0.170	0.077	−0.185	0.054	−0.136	0.157
∆FPG (mmol/L)	−0.071	0.463	0.012	0.901	−0.159	0.099
∆FINS (mU/L)	−0.217	0.024	−0.192	0.046	−0.235	0.014
∆ FC-p (pmol/L)	−0.195	0.042	−0.128	0.184	−0.230	0.016
∆Matsuda Index	0.062	0.522	−0.074	0.447	0.195	0.042
∆HOMA-IS	0.100	0.303	0.056	0.563	0.246	0.010
∆ ALT (U/L)	−0.046	0.632	−0.065	0.504	−0.006	0.948
∆ AST (U/L)	0.033	0.731	−0.029	0.766	0.087	0.367
∆ GGT (U/L)	0.150	0.120	0.077	0.426	0.171	0.076
∆ TC (mmol/L)	0.007	0.941	−0.072	0.455	0.065	0.499
∆ TG (mmol/L)	0.020	0.840	0.029	0.767	0.012	0.898
∆ HDL-c (mmol/L)	0.002	0.986	−0.062	0.520	0.029	0.765
∆ LDL-c (mmol/L)	0.089	0.357	0.034	0.725	0.125	0.194

∆, difference between selected variable values at one month and preoperatively; BMI, body mass index; FPG, fasting plasma glucose; FINS, fasting insulin; FC-p, fasting C-peptide; HOMA-IS: homeostasis model assessment of insulin sensitivity; ALT, alanine transaminase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; TC, total cholesterol; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin. Spearman r correlation, . Statistically significant values are indicated in bold.