International Journal of Endocrinology / 2020 / Article / Tab 1

Research Article

Characterization of Mineral and Bone Metabolism Biomarkers in a Chinese Consanguineous Twin Family with Primary Hypertrophic Osteoarthropathy

Table 1

Basic information and biomarkers for mineral and bone metabolism of all members in the twin family.

No.SexAge (y)Ca (mmol/L)P (mmol/L)PTH (pg/ml)25(OH)D (nmol/L)BGP (ng/ml)β-CTX (pg/ml)Uca/Ucr (mmol/mmol)

III-1M642.081.1931.8053.7711.67379.30.23
III-2F662.241.2842.2072.2512.44566.30.47
III-3M642.121.1022.4056.8513.40278.10.19
III-4F632.141.2229.4043.8810.44469.60.27
IV-1M422.201.4135.6057.0022.52387.80.20
IV-2M432.091.1932.6071.6714.40378.10.11
IV-3M442.101.3340.2057.8311.98281.00.15
IV-4F442.051.0918.2061.5810.99↓214.40.34
IV-5F422.131.3236.0058.2513.93209.60.12
IV-6F412.041.2239.8068.1713.54296.80.14
IV-7M412.201.0720.1057.4213.71330.40.21
V-3M182.131.5251.7037.10225.504112.00.63
#V-4M182.141.2439.0067.2937.77901.0↑0.23

Proband; #proband’s twin brother, 25(OH)D deficiency; 25(OH)D insufficiency. Abbreviations: Ca, calcium; P, phosphorus; PTH, parathyroid hormone; 25(OH)D, 25-hydroxyvitamin D; BGP, bone Gla-protein; β-CTX, C-terminal telopeptide of type I collagen; Uca/Ucr, urinary calcium/creatinine ratio. Reference range: Ca, 2.03–2.54 mmol/L; P, 0.87–1.45 mmol/L; PTH, 15–65 pg/ml; 25(OH)D, <50 nmol/L, deficiency; 50–75 nmol/L, insufficiency; >75 nmol/L, normal range; BGP, 11–43 ng/ml; β-CTX, before menopause, 30–573 pg/ml; postmenopause, 104–1008 pg/ml.

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