Parathyroid Hormone Reduction Predicts Transient Hypocalcemia after Total Thyroidectomy: A Single-Center Prospective Study

Table 2

The comparison between patients who developed hypocalcemia and normocalcemia on postoperative day 1.

Variables	Hypocalcemia	Normocalcemia
Gender (male)	7.84% (4/51)	28.57% (35/125)	0.004^a
Age (year)	45.00 (35∼53)	47.00 (37.5∼53)	0.841^b
PTH reduction (%)	86.19 (77.92∼91.17)	53.01 (33.26∼75.58)	<0.001^b
Tumor diameter (cm)	1.30 (0.70∼2.25)	0.90 (0.60∼1.50)	0.028^b
Tumor grade	1 (1∼4)	1 (1∼3)	0.405^b
Preoperative serum PTH (pg/ml)	44.90 (37.12∼64.38)	46.18 (37.56∼58.43)	0.893^b
Preoperative serum Ca (mmol/l)	2.32 (2.23∼2.41)	2.36 (2.29∼2.46)	0.034^b
POD1 serum PTH (pg/ml)	6.35 (4.00∼11.51)	22.06 (13.18∼31.53)	<0.001^b
POD1 serum Ca (mmol/l)	1.91 (1.84∼1.96)	2.15 (2.05∼2.25)	<0.001^b
Postoperative complications			<0.001^a
Convulsion	64.71% (33/51)	19.20% (24/125)
Numbness	35.19% (18/51)	9.60% (12/125)

POD1, postoperative day 1. ^aDifference between groups is tested by the χ [2] test; ^bdifference between groups is tested by the Mann–Whitney U test.