Research Article
Early Sialadenitis After Radioactive Iodine Therapy for Differentiated Thyroid Cancer: Prevalence and Predictors
Table 1
Characteristics of subjects with and without sialadenitis who received radioactive iodine for differentiated thyroid cancer.
| | | Total | Sialadenitis | value | | N = 174 | No N = 139 | Yes N = 35 |
| | Gender n (%) female | 124 (71.3) | 96 (69.1) | 28 (80.0) | 0.20 | | Age, mean (±SD) | 42.8 ± 14.4 | 43.0 ± 14.8 | 41.8 ± 13.1 | 0.65 | | Nationality n (%) | | | | | | Lebanese | 118 (67.8) | 100 (71.9) | 18 (51.4) | 0.02 | | Non-Lebanese | 56 (32.2) | 39 (28.1) | 17 (48.6) | | BMI, mean (±SD) | 28.6 ± 6.3 | 28.4 ± 6.4 | 29.2 ± 5.7 | 0.49 | | SBP, mean (±SD) | 125.1 ± 15.8 | 125.3 ± 15.9 | 124.4 ± 15.6 | 0.76 | | DBP, mean (±SD) | 79.4 ± 11.7 | 79.5 ± 11.8 | 79.2 ± 11.6 | 0.92 | | Tumor pathology | | | | | | PTC | 162 (93.1) | 130 (93.5) | 32 (91.4) | 0.57 | | FTC | 10 (5.7) | 7 (5.0) | 3 (8.6) | | Other | 2 (1.1) | 2 (1.4) | 0 (0.0) | | Recurrence, yes n (%) | 26 (14.9) | 23 (16.5) | 3 (8.6) | 0.24 | | Lymph node, yes n (%) | 89 (64.5) | 69 (62.7) | 20 (71.4) | 0.39 | | RAI dose n (%) | | | | | | 50 m/Cu | 40 (23.0) | 36 (25.9) | 4 (11.4) | | 100 m/Cu | 110 (63.2) | 84 (60.4) | 26 (74.3) | 0.18 | | 150 m/Cu | 24 (13.8) | 19 (13.7) | 5 (14.3) | | Thyrogen, yes | 7 (4.0) | 6 (4.3) | 1 (2.9) | 1.00 | | Pretherapy TSH (mIU/L), mean (±SD) | 83.9 ± 23.4 | 85.8 ± 21.7 | 76.6 ± 28.4 | 0.04 | | Pretherapy TSH (mIU/L) categorical | | | | | | <50 | 18 (11.0) | 12 (9.2) | 6 (17.6) | 0.11 | | 50–75 | 27 (16.5) | 19 (14.6) | 8 (23.5) | | >75 | 119 (72.6) | 99 (76.2) | 20 (58.8) | | Smoking, yes | 39 (22.5) | 31 (22.3) | 8 (23.5) | 0.88 | | Alcohol, yes | 23 (13.3) | 19 (13.7) | 4 (11.8) | 1.00 | | Dental problems, yes | 3 (2.2) | 3 (2.8) | 0 (0.0) | 1.00 | | Days off LT4, mean (±SD) | 26.8 ± 19.4 | 24.9 ± 16.3 | 33.0 ± 27.9 | 0.63 | | Days after surgery, mean (±SD) | 42.4 ± 38.3 | 44.3 ± 42.0 | 35.1 ± 15.9 | 0.12 | | Days off total, mean (±SD) | 39.7 ± 36.2 | 41.0 ± 39.5 | 34.7 ± 18.5 | 0.18 | | WBS result | | | | | | Negative | 19 (15.0) | 17 (17.5) | 2 (6.7) | 0.16 | | Positive | 98 (77.1) | 71 (73.3) | 27 (90.0) | | Distant | 10 (7.9) | 9 (9.2) | 1 (3.3) | | Treatment received | | | | | | NSAIDs | 20 (11.5) | 3 (2.2) | 17 (48.6) | 0.19 | | Steroids | 5 (2.9) | 2 (1.4) | 3 (8.6) | | Both | 6 (3.4) | 0 (0.0) | 6 (17.1) |
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10 patients did not have TSH levels available; 47 patients did not have WBS results available. |
