Liraglutide Promotes Osteoblastic Differentiation in MC3T3-E1 Cells by ERK5 Pathway

Figure 5

Liraglutide upregulated Col-1, OPG, and OCN protein expression. MC3T3-E1 cells were treated with different concentrations of liraglutide for 48 h, and then the protein expression of Col-1, OPG, and OCN was measured by western blot (a). Quantitative analysis of the protein level of Col-1 (b), OPG (c), and OCN (d) in MC3T3-E1 cells after treatment with liraglutide for 48 h.  < 0.01 compared with 0 nM,  < 0.01 compared with 10 nM, and  < 0.01 compared with 100 nM.

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