Research Article

Development and Validation of a Nomogram to Predict Type 2 Diabetes Mellitus in Overweight and Obese Adults: A Prospective Cohort Study from 82938 Adults in China

Table 2

Risk factors associated with T2DM among overweight and obesity population by Cox proportional hazards regression model

StratificationUnivariate analysisMultivariate analysis
HR (95% CI) valueHR (95% CI) value

Age (count)1.06 (1.04–1.08)<0.0011.04 (1.02–1.06)<0.001
BMI (count)1.18 (1.08–1.28)<0.0011.14 (1.04–1.24)0.004
FPG (count)4.60 (3.28–6.46)<0.0013.31 (2.28–4.81)<0.001
TC (count)1.62 (1.22–2.15)0.0011.52 (1.23–2.06)0.006
TG (count)1.18 (1.16–1.20)<0.0011.07 (1.05–1.10)<0.001
Family history of T2DM (yes vs. no)1.41 (1.08–1.82)<0.0011.46 (1.12–1.88)<0.001

The above variables were identified by LAOSSO regression; multiple cox regression adjusted the variables including age (count), BMI, FPG, TC, TG, and family history of T2DM. T2DM, type 2 diabetes mellitus; FPG, fasting plasma glucose; HR, hazard ratio; CI, confidence interval.