Research Article

Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents

Table 1

Demographic features of the study participants.

CharacteristicTotalNGTGlucose intolerance value (NGT versus IGT versus DM)
IGTDMSubtotal

Number (%)187 (100.0)115 (61.5)33 (17.6)39 (20.9)72

Age (years)12.51 ± 3.4511.76 ± 3.5612.83 ± 3.0414.47 ± 2.5413.72 ± 2.88<0.001

Sex (%)
 Female98 (52.4)51 (44.3)20 (60.6)27 (69.2)47 (65.3)0.004
 Male89 (47.6)64 (55.7)13 (39.4)12 (30.8)25 (34.7)

Family history of DM in the first-degree relatives63 (33.7)24 (20.9)16 (48.5)23 (59.0)39 (54.2)<0.001
 BMI (kg/m2)24.50 ± 5.1223.95 ± 4.6825.20 ± 6.1925.54 ± 5.2925.39 ± 5.680.170
  Normal59 (31.6)36 (31.3)8 (24.2)15 (38.5)23 (31.9)0.998
  Overweight42 (22.5)30 (26.1)5 (15.2)7 (17.9)12 (16.7)
  Obesity86 (46.0)49 (42.6)20 (60.6)17 (43.6)37 (51.4)

The data are presented as mean ± SD values. NGT, normal glucose tolerance; IGT, impaired glucose tolerance; DM, type 2 diabetes mellitus; BMI, body mass index; SD, standard deviation.