Research Article

Recurrence Factors and Characteristic Trends of Papillary Thyroid Cancer over Three Decades

Table 1

Demographic data of 235 papillary thyroid cancer patients.

Total (n = 235)No recurrence (n = 182)Persistence/recurrence (n = 53) value

Age at initial diagnosis (years)42.5 ± 14.341.8 ± 13.644.7 ± 16.30.180
 <55189 (80.4)154 (84.6)35 (66.0)
 55–7038 (16.2)23 (12.6)15 (28.3)
 >708 (3.4)5 (2.8)3 (5.7)
Female (%)192 (81.7)153 (84.1)39 (73.6)0.082
BMI (kg/m2)22.1 ± 3.822.9 ± 3.822.9 ± 3.60.925
ATA risk (%)0.013
 Low124 (52.8)105 (57.7)19 (35.8)
 Intermediate42 (17.8)31 (17.0)11 (20.8)
 High69 (29.4)46 (25.3)23 (43.4)
Size (cm)2.3 ± 1.42.2 ± 1.32.7 ± 1.70.031
 ≤150 (21.4)42 (23.1)8 (15.4)
 >1–276 (32.0)57 (31.3)19 (34.6)
 >2–490 (38.5)72 (39.6)18 (34.6)
 >419 (8.1)11 (6.0)8 (15.4)
Extrathyroidal extension (%)18 (7.7)12 (6.6)6 (11.5)0.238
8th AJCC staging (%)<0.001
 I211 (89.7)171 (94.0)40 (75.4)
 II19 (8.1)10 (5.5)9 (17.0)
 III2 (0.9)02 (3.8)
 IV3 (1.3)1 (0.5)2 (3.8)
Follow-up time (years)9.5 ± 7.79.4 ± 7.69.7 ± 7.80.769
Coexistence of Hashimoto’s thyroiditis (%)46 (19.6)44 (24.2)2 (3.8)<0.001

AJCC: the American Joint Committee on Cancer.