miR-124-3p Combined with ANGPTL2 Has High Diagnostic Values for Obese and Nonobese Polycystic Ovary Syndrome
Table 2
Comparison of clinical baseline data between obese and nonobese PCOS patients and healthy subjects.
Feature
Control-obese
PCOS-obese
Control-nonobese
PCOS-nonobese
Pa
Pb
Pc
(N = 32)
(N = 42)
(N = 68)
(N = 60)
General comparison
Age (year)
26 ± 3.6
26 ± 3.8
26 ± 3.5
26 ± 3.7
>0.9999
>0.9999
>0.9999
BMI (kg/m2)
26.46 ± 0.94
30.02 ± 1.66
21.03 ± 1.45
23.07 ± 1.40
<0.0001
<0.0001
<0.0001
Ferriman–Gallwey score
4.87 ± 1.74
7.79 ± 2.52
4.13 ± 1.67
5.92 ± 1.29
<0.0001
<0.0001
<0.0001
Lipid metabolism index
TC (mmol/L)
4.52 ± 0.86
4.86 ± 0.88
4.48 ± 0.63
4.63 ± 0.72
0.2198
0.6735
0.4269
TG (mmol/L)
1.28 ± 0.24
1.33 ± 0.28
1.22 ± 0.21
1.29 ± 0.25
0.8159
0.3643
0.845
Glucose metabolism index
HOMA-IR
2.47 ± 0.39
2.87 ± 0.66
2.39 ± 0.35
2.83 ± 0.65
0.0083
<0.0001
0.982
FBG (mmol/L)
5.13 ± 0.82
5.52 ± 0.94
4.82 ± 0.78
5.09 ± 0.84
0.2031
0.2734
0.058
FINS (mU/L)
10.86 ± 1.84
12.48 ± 2.03
9.96 ± 1.64
11.36 ± 2.01
0.0016
0.0002
0.0171
Sex hormone levels
T (ng/mL)
0.46 ± 0.12
0.63 ± 0.24
0.41 ± 0.12
0.53 ± 0.16
<0.0001
0.0003
0.0141
E2 (pg/mL)
48.34 ± 8.62
52.32 ± 9.03
48.26 ± 8.26
50.26 ± 8.86
0.2074
0.5616
0.6387
PRL (ng/mL)
11.86 ± 2.42
11.16 ± 1.16
11.68 ± 1.26
11.38 ± 1.08
0.1672
0.6438
0.8731
LH (mIU/mL)
6.46 ± 1.62
7.62 ± 2.61
5.84 ± 1.58
6.68 ± 2.48
0.0946
0.1172
0.126
FSH (mIU/mL)
6.35 ± 1.28
5.52 ± 1.12
6.64 ± 1.29
5.59 ± 1.12
0.0194
0.0067
0.31
LH/FSH
1.12 ± 0.38
1.28 ± 0.31
0.88 ± 0.13
1.08 ± 0.23
<0.0001
<0.0001
<0.0001
Inflammatory factor levels
TNF-α (pg/mL)
49.36 ± 4.26
64.68 ± 10.42
46.32 ± 4.03
57.28 ± 9.64
<0.0001
<0.0001
<0.0001
IL-6 (pg/mL)
45.62 ± 5.86
72.36 ± 12.64
38.69 ± 5.26
59.84 ± 11.08
<0.0001
<0.0001
<0.0001
Note. Pa, PCOS-obese group versus control-obese group; Pb, PCOS-nonobese group versus control-nonobese group; Pc, PCOS-obese group versus PCOS-nonobese group. indicated statistical significance. BMI = body mass index; TC = total cholesterol; TG = total triglyceride; HOMA-IR = HOMA insulin resistance; FBG = fasting blood glucose; FINS = fasting insulin; T = total testosterone; E2 = estradiol; PRL = prolactin; LH = luteinizing hormone; FSH = follicle-stimulating hormone.
