Resveratrol Alleviates Skeletal Muscle Insulin Resistance by Downregulating Long Noncoding RNA

Table 3

Top 30 significantly differentially expressed lncRNAs in mice.

LncRNA_id	log2FC (HFD versus CON)	value (HFD versus CON)	Up/down (HFD versus CON)	log2FC (HFD + RSV versus HFD)	value (HFD + RSV versus HFD)	Up/down (HFD + RSV versus HFD)
NONMMUT147944.1	7.361654305	3.08E−05	Up	−7.65705	2.59E−05	Down
NONMMUT018494.2	6.726119826	2.72E−30	Up	−6.63171	1.25E−30	Down
NONMMUT056862.2	6.372532912	0.000101	Up	−6.47057	0.000104	Down
NONMMUT001029.2	5.951073546	1.73E−06	Up	−6.20954	1.09E−06	Down
NONMMUT034722.2	5.925450571	5.74E−05	Up	−5.99116	5.98E−05	Down
NONMMUT042491.2	5.439454581	0.000152	Up	−6.0331	6.81E−05	Down
NONMMUT011659.2	5.319133003	0.000118	Up	−5.39538	0.000122	Down
NONMMUT028972.2	5.109498067	9.40E−05	Up	−5.33988	7.69E−05	Down
NONMMUT056994.2	4.330643092	1.11E−07	Up	−3.97586	2.22E−06	Down
NONMMUT044528.2	4.3149951	2.45E−05	Up	−4.67614	1.12E−05	Down
NONMMUT139818.1	4.27510251	5.42E−10	Up	−2.93598	3.09E−07	Down
NONMMUT006490.2	4.040499067	4.37E−05	Up	−4.25073	3.25E−05	Down
NONMMUT153460.1	3.987910041	1.14E−10	Up	−4.43375	1.79E−11	Down
NONMMUT047957.2	3.622830463	5.31E−12	Up	−2.17202	1.80E−06	Down
NONMMUT061044.2	3.580172631	0.000913	Up	−5.02265	0.000116	Down
NONMMUT041793.2	3.348027654	0.000102	Up	−4.15666	2.47E−06	Down
MSTRG.26789.5	3.346146359	4.90E−17	Up	−2.35799	1.25E−05	Down
NONMMUT141647.1	3.045932847	2.40E−05	Up	−3.7519	3.30E−05	Down
NONMMUT019242.2	2.994018555	1.34E−16	Up	−1.86027	2.37E−07	Down
NONMMUT054892.2	2.304363454	8.76E−08	Up	−1.99848	3.44E−05	Down
NONMMUT051479.2	2.213054794	0.00098	Up	−3.05151	3.84E−05	Down
NONMMUT003238.2	2.187198497	0.045286	Up	−5.56027	8.43E−05	Down
NONMMUT004274.2	2.077962645	1.51E−05	Up	−1.86821	0.000128	Down
NONMMUT006717.2	2.041245592	1.41E−06	Up	−2.02194	8.66E−06	Down
ENSMUST00000145549	1.981088074	3.80E−07	Up	−1.97828	7.99E−07	Down
NONMMUT071342.2	1.630473739	0.012079	Up	−3.80688	1.60E−13	Down
NONMMUT005295.2	1.449638857	1.11E−06	Up	−1.41758	2.03E−05	Down
NONMMUT070926.2	1.34488241	0.026106	Up	−2.66561	8.38E−08	Down
NONMMUT006953.2	1.275954985	0.000623	Up	−2.36716	2.40E−09	Down
NONMMUT044897.2	1.249501171	2.60E−05	Up	−1.43116	2.19E−05	Down
NONMMUT048831.2	−1.272978476	0.046708	Down	1.547263	0.000408	Up
NONMMUT018620.2	−1.425732816	0.032203	Down	1.762165	0.000445	Up
NONMMUT051818.2	−1.49981749	0.00019	Down	1.757541	0.000229	Up
NONMMUT148959.1	−1.821849383	0.022286	Down	2.39635	0.000835	Up
NONMMUT025210.2	−1.865766716	0.032229	Down	3.501751	1.41E−09	Up
NONMMUT024340.2	−1.99805347	6.44E−07	Down	1.727535	0.000114	Up
NONMMUT030788.2	−2.072643561	0.008364	Down	3.386966	6.32E−08	Up
NONMMUT083064.1	−2.184391746	0.02567	Down	3.578567	9.44E−07	Up
NONMMUT117757.1	−2.220356685	0.000126	Down	1.946318	0.000268	Up
NONMMUT145026.1	−2.225432629	0.005502	Down	2.733938	0.00075	Up
NONMMUT143802.1	−2.239123899	0.000257	Down	2.484837	0.000105	Up
NONMMUT081465.1	−2.275670974	0.000759	Down	2.214893	0.000569	Up
NONMMUT071570.2	−2.342779878	1.52E−05	Down	2.040383	7.76E−05	Up
NONMMUT145721.1	−2.395813608	0.00904	Down	3.144452	0.000475	Up
NONMMUT082610.1	−2.721997741	0.004713	Down	3.500026	3.04E−06	Up
NONMMUT032162.2	−2.756781381	0.000975	Down	3.252807	1.74E−06	Up
NONMMUT098269.1	−2.860045031	2.20E−09	Down	2.306565	0.000783	Up
NONMMUT119847.1	−2.871001568	6.07E−06	Down	2.197726	0.000589	Up
NONMMUT004497.2	−3.006495667	6.12E−06	Down	3.18202	2.60E−06	Up
NONMMUT144862.1	−3.021747289	0.000339	Down	2.825872	0.000763	Up
NONMMUT152140.1	−3.390813528	0.005418	Down	3.671173	0.000159	Up
NONMMUT145717.1	−3.429960838	0.003878	Down	4.82329	1.67E−05	Up
ENSMUST00000181045	−3.5774189	2.18E−05	Down	4.111429	1.20E−07	Up
MSTRG.8668.1	−3.650059914	8.30E−13	Down	2.418835	0.0002	Up
NONMMUT145909.1	−4.44549442	6.50E−05	Down	3.575655	3.04E−05	Up
NONMMUT008421.2	−4.495334741	0.000753	Down	5.182219	4.44E−06	Up
ENSMUST00000161890	−5.096061065	0.013794	Down	6.206952	7.53E−05	Up
NONMMUT128951.1	−5.845021433	2.88E−07	Down	4.876355	2.89E−05	Up
NONMMUT065156.2	−7.177240343	5.91E−41	Down	6.653339	2.22E−10	Up
NONMMUT026869.2	−8.335434963	1.59E−11	Down	7.485915	1.33E−06	Up

Top 30 upregulated or downregulated lncRNAs in three groups. HFD: high-fat diet; CON: control; RSV: resveratrol; lncRNA: long noncoding RNA.