TET3 Mediates 5hmC Level and Promotes Tumorigenesis by Activating AMPK Pathway in Papillary Thyroid Cancer

Figure 1

(a) The results of hydroxymethylation 5hmC staining in clinical specimens of papillary thyroid carcinoma showed that 5hmC was expressed in papillary thyroid carcinoma and normal thyroid tissues adjacent to the cancer, and the positive expression was brown (scale bar = 200 μm); (b) the results of genomic DNA 5hmC dot blot hybridization (dot blot) of papillary thyroid carcinoma;. (c) statistical analysis of genomic DNA 5hmC dot blot hybridization (dot blot) in papillary thyroid carcinoma; (d) real-time PCR was used to detect the expression of TET3 mRNA in papillary thyroid carcinoma and normal thyroid tissues; (e) western blot was used to detect the expression of TET3 in papillary thyroid carcinoma and adjacent normal thyroid samples. Sample size = 50 μg, internal reference: β-actin.

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