Research Article

Triglyceride-Glucose Index for the Diagnosis of Metabolic Syndrome: A Cross-Sectional Study of 298,652 Individuals Receiving a Health Check-Up in China

Table 3

Comparison of the demographic characteristics and biochemical indices between MS subgroups.

VariablesNon-MS (n = 285,967)MS (n = 12,685)χ2/t

TyG index8.58 ± 0.619.39 ± 0.59151.08<0.001
Sex235.10<0.001
 Female118,881 (41.57)6144 (48.44)
 Male167,086 (58.43)6541 (51.56)
Age (years)
 ≤45137,115 (47.95)1581 (12.46)7269.66<0.001
 46–69134,442 (47.01)9137 (72.03)
 >70144,10 (5.04)1967 (15.51)
BMI (kg/m2)22626.06<0.001
 <25196,774 (68.81)531 (4.19)
 ≥2589,193 (31.19)12,154 (95.81)
Drinking45.45<0.001
 0189,750 (66.35)8401 (66.23)
 126,925 (9.42)1708 (13.46)
 269,292 (24.23)2576 (20.31)
Smoking166.64<0.001
 0207,337 (72.50)9809 (77.33)
 162,489 (21.85)2415 (19.04)
 216,141 (5.64)461 (3.63)
Hypertension44618.30<0.001
 No242,290 (84.73)1321 (10.41)
 Yes43,677 (15.27)11,364 (89.59)
Hyperlipidemia17664.97<0.001
 No264,967 (92.66)7421 (58.50)
 Yes21,000 (7.34)5264 (41.50)
Hyperglycemia61940.62<0.001
 No261,355 (91.39)2390 (18.84)
 Yes24,612 (8.61)10,295 (81.16)
eGFR1884.72<0.001
 <6054,451 (19.04)4403 (34.71)
 ≥60231,516 (80.96)8282 (65.29)
SBP (mm Hg)118.00 ± 15.95143.20 ± 15.80174.28<0.001
DBP (mm Hg)76.90 ± 9.6389.22 ± 9.83138.23<0.001
TG (mmol/L)1.52 ± 1.192.54 ± 1.8561.88<0.001
TC (mmol/L)4.61 ± 0.895.09 ± 1.0053.60<0.001
HDL_C (mmol/L)1.38 ± 0.351.26 ± 0.2941.42<0.001
LDL_C (mmol/L)2.55 ± 0.772.73 ± 0.8921.46<0.001
FBG (mmol/L)5.31 ± 1.017.15 ± 2.02101.68<0.001

MS, metabolic syndrome; TyG, triglyceride-glucose; BMI, body mass index; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FBG, fasting blood glucose.