Value of Contrast-Enhanced Ultrasound in Adjusting the Classification of Chinese-TIRADS 4 Nodules
Table 1
The diagnostic efficiency of the C-TIRADS 4 before and after the adjustment based on CEUS.
Nodules
Total before the adjustment
Total after the adjustment
Group I before the adjustment
Group I after the adjustment
Group II before the adjustment
Group II after the adjustment
n
125
125
55
55
70
70
Sensitivity (%)
83.6(56/67)
91.0(61/67)
84.6(22/26)
84.6(22/26)
82.9(34/41)
95.1(39/41)
Specificity (%)
63.8(37/58)
82.8(48/58)
62.1(18/29)
75.9(22/29)
65.5(19/29)
89.7(26/29)
Accuracy (%)
74.4(93/125)
87.2(109/125)
72.7(40/55)
80.0(44/55)
75.7(53/70)
92.9(65/70)
PPV (%)
72.7(56/77)
85.9(61/71)
66.7(22/33)
75.9(22/29)
77.3(34/44)
92.9(39/42)
NPV (%)
77.1(37/48)
88.9(48/54)
81.8(18/22)
84.6(22/26)
73.1(19/26)
92.9(26/28)
AUC
0.737
0.869
0.733
0.802
0.742
0.924
Z
3.288
1.394
2.931
0.001
0.163
0.003
C-TIRADS: the Chinese-Thyroid Imaging Report and Data System; CEUS: contrast-enhanced ultrasound; PPV: positive predictive value; NPV: negative predictive value; AUC: area under the ROC curve.
