Insulin-induced Lipohypertrophy in Patients with Type 1 Diabetes Mellitus Treated with an Insulin Pump
Table 2
Univariate and multivariate models for risk factors of 5 and more LH lesions.
Variable
OR per
Univariate
Multivariate
OR (95% CI)
OR (95% CI)
Age
1 year
1.003 (0.95–1.06)
0.91
Male sex
No/Yes
0.95 (0.39–2.31)
0.91
BMI
kg/m2
1.14 (1.00–1.31)
0.055
1.14 (0.98–1.33)
0.09
Diabetes duration
1 year
1.00 (0.94–1.06)
0.95
Duration of CSII
1 year
1.02 (0.93–1.13)
0.60
Regular changing of infusion sites
No/Yes
0.73 (0.21–2.44)
0.61
Changing infusion set every 3 day or more frequently
No/Yes
1.35 (0.55–3.32)
0.51
Length of cannula ≥9 mm
No/Yes
1.59 (0.65–3.96)
0.31
HbA1c
%
1.23 (0.85–1.84)
0.29
Dose of insulin >0.7 IU/kg
No/Yes
3.69 (1.43–10.01)
0.008
3.37 (1.27–9.31)
0.016
Dose of insulin
IU
1.05 (1.02–1.09)
0.002
In the multivariate logistic regression model the variables with -value <0.10 based on univariate logistic models were included (except for daily insulin dose because of including dose of insulin per kg body weight). OR, odds ratio; CI, confidence interval; for other abbreviations see Table 1.