Research Article

Insulin-induced Lipohypertrophy in Patients with Type 1 Diabetes Mellitus Treated with an Insulin Pump

Table 2

Univariate and multivariate models for risk factors of 5 and more LH lesions.

VariableOR perUnivariateMultivariate
OR (95% CI)OR (95% CI)

Age1 year1.003 (0.95–1.06)0.91
Male sexNo/Yes0.95 (0.39–2.31)0.91
BMIkg/m21.14 (1.00–1.31)0.0551.14 (0.98–1.33)0.09
Diabetes duration1 year1.00 (0.94–1.06)0.95
Duration of CSII1 year1.02 (0.93–1.13)0.60
Regular changing of infusion sitesNo/Yes0.73 (0.21–2.44)0.61
Changing infusion set every 3 day or more frequentlyNo/Yes1.35 (0.55–3.32)0.51
Length of cannula ≥9 mmNo/Yes1.59 (0.65–3.96)0.31
HbA1c%1.23 (0.85–1.84)0.29
Dose of insulin >0.7 IU/kgNo/Yes3.69 (1.43–10.01)0.0083.37 (1.27–9.31)0.016
Dose of insulinIU1.05 (1.02–1.09)0.002

In the multivariate logistic regression model the variables with -value <0.10 based on univariate logistic models were included (except for daily insulin dose because of including dose of insulin per kg body weight). OR, odds ratio; CI, confidence interval; for other abbreviations see Table 1.