Insulin-induced Lipohypertrophy in Patients with Type 1 Diabetes Mellitus Treated with an Insulin Pump
Table 3
Univariate and multivariate models for risk factors of advanced LH based on the authorial scale (6–8 points).
Variable
OR per
Univariate
Multivariate
OR (95% CI)
OR (95% CI)
Age
1 year
1.04 (0.98–1.09)
0.18
Male sex
No/Yes
1.29 (0.52–3.24)
0.58
BMI
kg/m2
1.22 (1.06–1.43)
0.007
1.14 (0.96–1.37)
0.15
Diabetes duration
1 year
1.05 (0.99–1.12)
0.08
1.06 (0.99–1.14)
0.13
Duration of CSII
1 year
0.99 (0.90–1.09)
0.82
Regular changing of infusion sites
No/Yes
0.67 (0.17–2.28)
0.53
Changing infusion set every 3 day or more frequently
No/Yes
0.84 (0.33–2.11)
0.72
Length of cannula ≥9 mm
No/Yes
4.01 (1.52–11.39)
0.007
3.44 (1.11–11.74)
0.038
HbA1c
%
1.11 (0.76–1.61)
0.57
Dose of insulin >0.7 IU/kg
No/Yes
3.89 (1.47–10.96)
0.008
4.81 (1.53–17.22)
0.010
Dose of insulin
IU
1.03 (1.004–1.06)
0.03
In the multivariate logistic regression model the variables with -value <0.10 based on univariate logistic models were included (except for daily insulin dose because of including dose of insulin per kg body weight). For abbreviations see Tables 1 and 2.