International Journal of Endocrinology

Sex/Gender Differences in Metabolism and Behavior: Influence of Sex Chromosomes and Hormones


Publishing date
04 Sep 2015
Status
Published
Submission deadline
15 May 2015

Lead Editor

1Miami University, Oxford, USA

2North Carolina A&T State University, Greensboro, USA

3University of the Pacific, Stockton, USA


Sex/Gender Differences in Metabolism and Behavior: Influence of Sex Chromosomes and Hormones

Description

Significant sex differences exist in the regulation of behavior and metabolism as well as development and progression of metabolic diseases such as obesity, diabetes, cardiovascular diseases, eating disorders, some types of gastrointestinal and reproductive disorders, cancers, and psychological and psychiatric disorders. Less attention has been paid to sex differences in various metabolic systems and to the potential influence of sex hormones on the above-mentioned metabolic diseases. The importance of sex differences and sex steroid effects lies both in inherent differences in structure, physiology, and function of different organ systems throughout the lifespan and in the impact of hormonal changes at different life stages, such as puberty, pregnancy, aging, and menopause. Recent research efforts and findings have greatly advanced our understanding of the roles of sex and sex hormones in physiological processes and functions as well as pathological development and progression of metabolic diseases. Nevertheless, many knowledge gaps and paradoxes still remain. In order to effectively develop novel therapeutic strategies that benefit patients of both sexes, a better understanding of mechanisms underlying the sex differences in behavior and metabolism and the influence of sex steroids is required.

Therefore, we invite investigators to contribute original research articles and reviews from basic and translational preclinical studies that stimulate the continuing efforts to understand the genetic, behavioral, physiological, cellular, and molecular mechanisms underlying sex-based differences in behavior and metabolism under physiological and pathological conditions.

Potential topics include, but are not limited to:

  • Inherent sex-based differences in structure, physiology, and function of various organs related to the endocrine system
  • Novel pathways employed by sex hormones and their receptors on the structure and function of multiple organ systems and behaviors
  • Impact of hormonal changes at different life stages (e.g., puberty, pregnancy, aging, and menopause) on different metabolic systems and behaviors
  • Central and peripheral actions of sex hormones (e.g., estrogen, progesterone, and testosterone), their receptors, and intracellular signaling pathways in the regulation of different metabolic systems and behaviors and related disease development and potential treatment strategies
  • Latest technologies for evaluating and measuring sex-based differences in basic and translational preclinical research

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 245949
  • - Editorial

Sex/Gender Differences in Metabolism and Behavior: Influence of Sex Chromosomes and Hormones

Haifei Shi | Lynda M. Brown | Roshanak Rahimian
  • Special Issue
  • - Volume 2015
  • - Article ID 615356
  • - Review Article

A Role for Estrogen in Schizophrenia: Clinical and Preclinical Findings

Andrea Gogos | Alyssa M. Sbisa | ... | Brian Dean
  • Special Issue
  • - Volume 2015
  • - Article ID 218219
  • - Research Article

Sodium Valproate Enhances the Urethane-Induced Lung Adenomas and Suppresses Malignization of Adenomas in Ovariectomized Female Mice

Donatas Stakisaitis | Raminta Mozuraite | ... | Angelija Valanciute
  • Special Issue
  • - Volume 2015
  • - Article ID 949085
  • - Review Article

Regulation of Estrogen Receptor α Expression in the Hypothalamus by Sex Steroids: Implication in the Regulation of Energy Homeostasis

Xian Liu | Haifei Shi
  • Special Issue
  • - Volume 2015
  • - Article ID 294278
  • - Review Article

Sex Hormones and Their Receptors Regulate Liver Energy Homeostasis

Minqian Shen | Haifei Shi
  • Special Issue
  • - Volume 2015
  • - Article ID 854530
  • - Review Article

Role of Sex Hormones in the Development and Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma

Maurizio Montella | Giovanni D’Arena | ... | Aldo Giudice
  • Special Issue
  • - Volume 2015
  • - Article ID 149408
  • - Research Article

17β Estradiol Modulates Perfusion Pressure and Expression of 5-LOX and CYP450 4A in the Isolated Kidney of Metabolic Syndrome Female Rats

A. M. Zúñiga-Muñoz | V. Guarner Lans | ... | I. Pérez-Torres
International Journal of Endocrinology
 Journal metrics
Acceptance rate30%
Submission to final decision72 days
Acceptance to publication39 days
CiteScore2.350
Impact Factor2.287
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