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International Journal of Electrochemistry
Volume 2011, Article ID 512692, 8 pages
Research Article

Voltammetric Detection of Dopamine in Presence of Ascorbic Acid and Uric Acid at Poly (Xylenol Orange) Film-Coated Graphite Pencil Electrode

Department of P. G. Studies and Research in Industrial Chemistry, Jnana Sahyadri, Kuvempu University, Shankaraghatta-577 451, Shimoga, Karnataka (S), India

Received 17 February 2011; Accepted 6 April 2011

Academic Editor: Bengi Uslu

Copyright © 2011 Umesh Chandra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Poly (xylenol orange) film-coated graphite pencil electrode was fabricated for the detection of dopamine in the presence of ascorbic acid and uric acid in phosphate buffer solution of pH 7. The redox peaks obtained at modified electrode shows a good enhancement. The scan rate effect was found to be a diffusion-controlled electrode process. The electrochemical oxidation of dopamine was depended on pH, and the limit of detection was found to be 9.1 10−8 M. The simultaneous study gave and excellent result with great potential difference between dopamine and other bioactive organic molecules by using both cyclic voltammetric and differential pulse voltammetric techniques. The present modified graphite electrode was applied to the detection of dopamine in the injection samples, and the recovery obtained was satisfactory.