Automated Online Solid-Phase Extraction Coupled with Sequential Injection-HPLC-EC System for the Determination of Sulfonamides in Shrimp

Table 4

Determination of SAs levels in shrimp samples by the traditional HPLC-MS method and the developed online SPE-HPLC-EC method.

Spiked level (μg g^−1)	Analytes	Online SPE-HPLC-EC method (conc. ± SD*, μg g^−1)	HPLC-MS (conc. ± SD*, μg g^−1)
	SMZ	1.76 ± 0.11	1.77 ± 0.10
	SMM	2.01 ± 0.13	1.82 ± 0.11
2	SMX	2.13 ± 0.11	2.04 ± 0.11
	SDM	2.04 ± 0.06	1.70 ± 0.09
	SQ	2.11 ± 0.03	1.49 ± 0.09
	SMZ	3.45 ± 0.11	4.39 ± 0.14
	SMM	3.41 ± 0.15	4.44 ± 0.14
4	SMX	3.76 ± 0.08	4.57 ± 0.16
	SDM	3.72 ± 0.16	4.34 ± 0.14
	SQ	3.65 ± 0.05	4.34 ± 0.14
	SMZ	5.85 ± 0.13	6.56 ± 0.18
	SMM	6.28 ± 0.21	6.30 ± 0.18
6	SMX	5.74 ± 0.12	6.61 ± 0.18
	SDM	6.06 ± 0.34	6.02 ± 0.17
	SQ	6.15 ± 0.07	5.79 ± 0.15

*SD: standard deviation (𝑛=3).