International Journal of Electrochemistry / 2018 / Article / Tab 1

Research Article

A New Approach for the Determination of Benzocaine and Procaine in Pharmaceuticals by Single-Sweep Polarography

Table 1

Brief description of some methods for determination of BC and PC.

AnestheticMethodLinear rangeLOQLODObjects analyzedReferences

PCHPLC-UV0.05 – 5.0 μg /mL0.05 μg/mLhuman plasma[6]
PCHPLC – MS – ESI10 – 100 ng / mL10.0 ng/mL0.100 ng/mLserum of human blood[7]
BCSP10 – 25 μg / L[8]
PCDPV3 – 50 μМ0.91 μМcommercial pharmaceutical samples[22]
PCDSWV1 – 250 μМ1.35 μМ0.4 μМcommercial pharmaceutical samples[22]
BC1.0 – 100 μМ0.83 μM0.25 μMpharmaceutical products[23]
BCFIA–AD
HPLC–AD
0.2 – 100
0.2 – 100 μM

0.19
0.20 μM
[24]
BCBIA–AD0.1 – 8 μM0.0302 μM[25]
BCDPV
SWV
0.1 – 400 μM
0.4 – 200 μM
0.27 μM
0.32 μM
0.08 μM
0.1 μM
pharmaceutical samples, spiked urine samples[26]

BIA–AD: batch injection analysis with amperometric detection; DPV: differential pulse voltammetry; DSWV: differential square wave voltammetry; FIA–AD – flow injection analysis with amperometric detection; HPLC: AD with amperometric detection; HPLC–MS–ESI: high-performance liquid chromatography–tandem mass spectrometry with electrospray ionization; HPLC-UV: high-performance liquid chromatography with ultraviolet detection; SP: spectrophotometry.

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