Research Article

Dissolution of Lipid-Based Matrices in Simulated Gastrointestinal Solutions to Evaluate Their Potential for the Encapsulation of Bioactive Ingredients for Foods

Table 2

Composition of the solutions used to prepare the simulated gastrointestinal solutions and amounts required to prepare the gastric secretion (GS) and duodenum secretion (DS) media.

SalivaBasal gastric secretionsActive gastric secretionsBasal pancreatic secretionsLipaseActive pancreatic secretionsBile

Composition6 mM KCl20 mM HCl15 mM KCl100 mM NaCl0.9 mM HCl20 mM NaCl100 g/L
Oxgall
62 mM 
NaHCO3
10 mM KCl5 mM NaCl50 mM 
NaHCO3
10 mM KCl140 mM 
NaHCO3
15 mM NaCl90 mM NaCl150 mM
 HCL
10 mM KCl90 mM NaCl10 mM KCl
6 mM 
K2HPO4·3H2O
100 U/mL
Pepsin
1000 U/mL
Pepsin
1.2 g/L
pancreatin
300 U/mL lipases12 g/L
pancreatin
0.0066 mM 
CaCl2·2H2O
2.2 g/L Mucin
2000 U/mL 
-amylase

Amount of GS medium (mL)39163511

Amount of DS medium (mL)17715353717