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Comparative and Functional Genomics
Volume 3, Issue 2, Pages 97-100
http://dx.doi.org/10.1002/cfg.165

A European Pathogenic Microorganism Proteome Database: Construction and Maintenance

1Max Planck Institute for Infection Biology, Core Facility Bioinformatics, Berlin, Germany
2Algorithmus, Berlin, Germany
3Max Planck Institute for Infection Biology, Core Facility Protein Analysis, Schumannstr. 20–21, Berlin D-10117, Germany

Received 18 February 2002; Accepted 19 February 2005

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A relational database structure based on MS-Access and MySQL to store and manage proteomics data was established. This system may be used to publish two-dimensional electrophoretic proteomics data, and also may be accessed by external users who want to compare their own data with those in the databases. The maintenance of the database is managed centrally. The producers of proteomics data do not need to construct a database themselves. Users can introduce mass spectra into the database, which allows the searching of peptide mass fingerprints against their own protein sequence databases. The first release published in January 2002 contains data from Mycobacterium tuberculosis, Helicobacter pylori, Borrelia garinii, Francisella tularensis, Chlamydia pneumoniae, Mycoplasma pneumoniae, Jurkat T-cells and mouse mammary gland projects (http://www.mpiib-berlin. mpg.de/2D-PAGE/).