International Journal of Genomics

International Journal of Genomics / 2002 / Article

Conference Review | Open Access

Volume 3 |Article ID 837979 | 3 pages | https://doi.org/10.1002/cfg.193

Microarray Analysis of Bacterial Gene Expression: Towards the Regulome

Received31 May 2002
Accepted10 Jun 2002

Abstract

Microarray technology allows co-regulated genes to be identified. In order to identify genes that are controlled by specific regulators, gene expression can be compared in mutant and wild-type bacteria. However, there are a number of pitfalls with this approach; in particular, the regulator may not be active under the conditions in which the wild-type strain is cultured. Once co-regulated genes have been identified, proteinbinding motifs can be identified. By combining these data with a map of promoters, or operons (the operome), the regulatory networks in the cell (the regulome) can start to be built up.

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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