International Journal of Genomics

International Journal of Genomics / 2004 / Article

Conference paper | Open Access

Volume 5 |Article ID 613217 |

John Skilling, Richard Denny, Keith Richardson, Phillip Young, Thérèse McKenna, Iain Campuzano, Mark Ritchie, "ProbSeq—A Fragmentation Model for Interpretation of Electrospray Tandem Mass Spectrometry Data", International Journal of Genomics, vol. 5, Article ID 613217, 8 pages, 2004.

ProbSeq—A Fragmentation Model for Interpretation of Electrospray Tandem Mass Spectrometry Data

Received31 Oct 2003
Revised18 Nov 2003
Accepted26 Nov 2003


We describe a probabilistic peptide fragmentation model for use in protein databank searching and de novo sequencing of electrospray tandem mass spectrometry data. A probabilistic framework for tuning of the model using a range of well-characterized samples are introduced. We present preliminary results of our tuning efforts.

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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