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Comparative and Functional Genomics
Volume 2008, Article ID 254836, 12 pages
http://dx.doi.org/10.1155/2008/254836
Research Article

Effects of Subminimum Inhibitory Concentrations of Antibiotics on the Pasteurella multocida Proteome: A Systems Approach

1College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA
2Mississippi State University Institute for Digital Biology, Mississippi State University, Mississippi State, MS 39762, USA
3Mississippi Agriculture and Forestry Experiment Station, Mississippi State University, Mississippi State, MS 39762, USA
4MSU Life Sciences and Biotechnology Institute, Mississippi State University, Mississippi State, MS 39762, USA

Received 6 December 2007; Accepted 19 February 2008

Academic Editor: John Parkinson

Copyright © 2008 Bindu Nanduri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

All proteins identified in this study are listed in Supplementary Table 1. Proteins with significant quantitative changes in expression in response to sub-MICs of AMX, CTC, or ENR are listed in Supplementary Table 2. Protein interaction networks built with significant changes in expression with sub-MICs shown in Table 3 are included in the supplementary figure. This figure shows changes in protein expression in response to sub-MICs of AMX, CTC, and ERN. Red and green indicate significant increase and decrease in expression, respectively. Proteins whose expression did not change (pink) and proteins in the network not identified in our datasets (gray) are also included.

  1. Supplementary Table 1
  2. Supplementary Table 2
  3. Supplementary Figure