Evolutionary Conservation Levels of Subunits of Histone-Modifying Protein Complexes in Fungi

Figure 2

Boxplots of evolutionary conservation levels of subunits of histone-modifying protein complexes. Based on the E values of the BLASTP search results, I classified 6 evolutionary conservation levels and scored them as follows: score 0, not detected; score 1, 𝐸 value >10⁰; score 2, 10⁻⁵⁰<𝐸 value ≤10⁰; score 3, 10⁻¹⁰⁰<𝐸 value ≤10⁻⁵⁰; score 4, 10⁻¹⁵⁰<𝐸 value ≤10⁻¹⁰⁰; score 5, 𝐸 value ≤10⁻¹⁵⁰. Each circle indicates the total of the scores of each protein. Top and bottom boxplots are based on the Saccharomyces and Schizosaccharomyces proteins, respectively. Boxes are composed of medians with first and third quartiles from the scores of the subunits. HATc, histone acetyltransferase (HAT) catalytic subunits; HATa, HAT-associated subunits; HDACc, histone deacetylase (HDAC) catalytic subunits; HDACa, HDAC-associated subunits; HMTc, histone methyltransferase (HMT) catalytic subunits; HMTa, HMT-associated subunits; and HDMTc, histone demethylase catalytic subunits.

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