Evolutionary Conservation Levels of Subunits of Histone-Modifying Protein Complexes in Fungi

Figure 3

Boxplots of combined evolutionary conservation levels of Saccharomyces and Schizosaccharomyces subunits of histone-modifying protein complexes. Based on the E values of the BLASTP search results, I classified 6 evolutionary conservation levels and scored them as follows: score 0, not detected; score 1, 𝐸 value >10⁰; score 2, 10⁻⁵⁰<𝐸 value ≤10⁰; score 3, 10⁻¹⁰⁰<𝐸 value ≤10⁻⁵⁰; score 4, 10⁻¹⁵⁰<𝐸 value ≤10⁻¹⁰⁰; score 5, 𝐸 value ≤10⁻¹⁵⁰. Each circle indicates the total of the scores of each protein. Boxes are composed of medians with first and third quartiles from the scores of the subunits. HATc, histone acetyltransferase (HAT) catalytic subunits; HATa, HAT-associated subunits; HDACc, histone deacetylase (HDAC) catalytic subunits; HDACa, HDAC-associated subunits; HMTc, histone methyltransferase (HMT) catalytic subunits; HMTa, HMT-associated subunits; HDMTc, histone demethylase catalytic subunits.