Research Article

Molecular Diversity of the Antimicrobial Domain of Beta-Defensin 3 and Homologous Peptides

Figure 5

Sequence logos generated for each antimicrobial-domain showing the divergence of amino acid residue in 3 and homologous peptides. Red arrows show amino acids subject to positive selection. Primate-, ungulate-, cow-, and rodent-BDEF3 clusters have different amino acid residue variations. This analysis demonstrates that eleven amino acid residues of the antimicrobial domain have been mutated by positive selection to confer BDEF3 niche specialization.
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