Research Article

Applications of Different Weighting Schemes to Improve Pathway-Based Analysis

Table 9

Top 33 type II diabetes pathways selected in the random forests under uniform weight and RWM scheme.

IndexUniform weightRWM scheme
RankPIDNo. of genesOOB (%)RankPIDNo. of genesOOB (%)

1179330.261140220.11
224180.292113260.14
32140220.29219210.14
44361160.31410650.17
5412440.315117260.17
642301210.31414470.17
77560.34416380.17
8716490.344164260.17
97321570.34417630.17
10746360.344197110.17
117511850.34423530.17
127109910.344244460.17
13714140.344245110.17
1472291330.344250120.17
15726740.34425110.17
1616120.374254250.17
1716630.374274160.17
181611150.37427590.17
191613920.3719120.20
2016372350.37194180.20
2116402400.3719560.20
2216491880.371911150.20
2316591940.371924140.20
24167630.37194220.20
251614470.3719521220.20
261616220.371969200.20
2716173110.37197410.20
2816194130.37197860.20
2916201190.37198050.20
301620730.37198580.20
3116209210.371986390.20
3216227130.371998710.20
3316228430.371999130.20

Total205011.295785.86
Average640.35180.18