Review Article

Versatility of RNA-Binding Proteins in Cancer

Figure 1

Schematic representation of the 4 RBPs discussed in this paper: Sam68, eIF4E, La, and HuR; RBDs are depicted in light gray. RRM: RNA recognition motif; GSG: GRP33/SAM68/GLD-1 domain, composed of a KH domain (KH) flanked by N-terminal (NK) and C-terminal (CK) extensions; LA: La motif. Phosphorylation sites of La are indicated in black (P0–P5). Nuclear localization signals (NLSs) are represented in dark gray. The number of amino acids of each protein is indicated.
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