475731.fig.003a
(a)
475731.fig.003b
(b)
Figure 3: Impact of uAUG sequences on translation regulation. (a) Comparison of luciferase levels obtained for constructs having the 5′ UTR of the gene ACT (control) and genes containing uAUG: WBSCR16, MFSD5, and BCL2L13. (b) Deletion or mutation of uAUG sequence present in genes WBSCR16, MFSD5 and BCL2L13 reverts translation repression as seen as an increase in luciferase activity.