XRCC7 rs#7003908 Polymorphism and Helicobacter pylori Infection-Related Gastric Antrum Adenocarcinoma

Table 5

Joint effects of XRCC7 rs#7003908 polymorphism and XRCC3 rs#861539 on GAA risk.

rs#861539	rs#7003908	Controls (𝑛=927)		Cases (𝑛=642)		OR (95% CI)^a	𝑃trend
		𝑛	%	𝑛	%
CC	TT	477	51.5	136	21.2	Reference
	TG/GG	113	12.2	94	14.6	2.73 (1.89–3.94)	9.39 × 10^−8
CT/TT	TT	46	5.0	24	3.7	0.60 (0.34–1.05)	0.08
	TG/GG	291	31.4	388	60.4	3.32 (2.54–4.34)	2.15 × 10^−18

aOR conditional on matched set adjusted for cagA status.
Likelihood ratio test for gene-gene interaction, OR = 1.49 (1.39–1.56), P = 1.12 × 10⁻³⁷.