Table 3: Stratification analyses between TSP-1-1223 A/G polymorphism and risk of bladder cancer.

VariablesGenotypes (cases/controls)
Cases/controlsAA + AGGG Crude OR (95% CI) Adjusted OR (95% CI)b
% %

Total
Age (year)
 <65289/331243/28984.1/87.346/4215.9/12.70.2511.30 (0.81–2.10)0.1281.38 (0.86–2.25)
 ≥65320/339289/30390.3/89.431/36 9.7/10.60.6920.90 (0.53–1.55)0.7190.94 (0.55–1.61)
Sex
 Male484/506423/45787.4/90.361/4912.6/9.70.1441.34 (0.89–2.05)0.1271.39 (0.91–2.13)
 Female125/164109/13587.2/82.316/2912.8/17.70.2570.68 (0.33–1.38)0.4950.78 (0.38–1.60)
Smoking status
 Never317/426278/37787.7/88.539/4912.3/11.50.7381.08 (0.67–1.73)0.3811.25 (0.76–2.05)
 Ever292/244254/21586.6/88.138/2913.4/11.90.6941.11 (0.64–1.93)0.7471.10 (0.63–1.91)
Drinking status
 No418/482367/42387.8/87.851/5912.2/12.20.9861.00 (0.65–1.52)0.6441.11 (0.71–1.73)
 Yes191/188165/16986.4/89.926/1913.6/10.10.2911.40 (0.71–2.79)0.3961.34 (0.68–2.64)
Family history of cancer
 No440/622385/54787.5/87.955/7512.5/12.10.8291.04 (0.70–1.53)0.5581.12 (0.76–1.65)
 Yes169/48147/4587.0/93.722/313.0/6.30.1952.24 (0.63–12.2)0.2842.02 (0.56–7.26)

CI: confidence interval; OR: odds ratio.
Two-sided test for either genotype distributions or allele frequencies between the cases and controls.
bAdjusted for age, gender, smoking, drinking status, and family history of cancer in logistic regression model.