Research Article

A Promoter Region Polymorphism in PDCD-1 Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China

Table 4

Estimated haplotype frequencies and the association analysis with RA.

HaplotypeSequenceCasesControlsTotalOR (95% CI) value

1ATC0.41080.40610.40811.00
2GCC0.25830.19190.22481.28 (0.94–1.73)0.11
3GCT0.21270.20660.20980.98 (0.72–1.32)0.87
4GTC0.05230.04620.04971.04 (0.53–2.02)0.91
5ACT0.0190.08210.04630.23 (0.10–0.53)
6ACC0.01380.04200.02800.32 (0.11–0.96)0.043*
7ATT0.02690.01390.02101.61 (0.52–5.02)0.41
Rare0.00811.55 (0.27–8.96)0.68
Global haplotype association P value: 0.0015*

OR: odds ratio; 95% CI: 95% confidence intervals. .
Rare haplotypes were pooled together in a group.