Associations of CTLA4 Gene Polymorphisms with Graves’ Ophthalmopathy: A Meta-Analysis

Table 2

Distribution of CTLA4 49A/G alleles among GO and controls in the included studies.

First author	Country	A/A (𝑛)		A/G (𝑛)		G/G (𝑛)
		GO	Non-GO	GO	Non-GO	GO	Non-GO
Villanueva (2000) [16]	USA	26	16	42	25	17	11
Allahabadia (2001) [17]	UK	53	83	82	180	26	60
Zaletel (2002) [18]	Slovenia	11	14	17	17	5	3
Esteghamati (2009) [24]	Iran	48	66	43	28	14	6
Bednarczuk (2003) [19]	Poland	27	48	41	82	27	39
Vaidya (2003) [11]	UK	27	61	62	77	40	34
Frydecka (2004) [13]	Poland	11	21	29	21	10	7
Petrone (2005) [20]	Italy	NA	NA	NA	NA	NA	NA
Han (2006) [21]	China	18	14	55	39	69	66
Zhang (2006) [22]	China	1	1	11	18	21	37
Chong (2008) [23]	China	1	0	9	8	24	14
Bednarczuk (2003) [19]	Japan	12	16	41	99	46	105
Park (2000) [15]	Korea	1	3	10	15	15	29

NA: not available.