Phylogenomic and Molecular Demarcation of the Core Members of the Polyphyletic Pasteurellaceae Genera Actinobacillus, Haemophilus, and Pasteurella

Figure 4

A partial sequence alignment of Menaquinone-specific isochorismate synthase showing a 4-amino-acid insertion identified in all members of Pasteurella sensu stricto. This insertion was not found in the homologues from any member of the genus Pasteurella that was not part of the “sensu stricto” clade or any other member of the Gammaproteobacteria. Sequence information for other CSIs specific to Pasteurella sensu stricto is presented in Supplemental Figures  9–13 and their characteristics are summarized in Table 2.