Phylogenomic and Molecular Demarcation of the Core Members of the Polyphyletic Pasteurellaceae Genera Actinobacillus, Haemophilus, and Pasteurella

Table 1

Genome characteristics of the sequenced Pasteurellaceae included in our analyses.

Organism name	BioProject	Size; (Mb)	Proteins	G-C; (%)	References
Actinobacillus pleuropneumoniae L20	CP000569	2.27	2013	41.3	[40]
Actinobacillus pleuropneumoniae serovar 3 str. JL03	CP000687	2.24	2036	41.2	[41]
Actinobacillus pleuropneumoniae serovar7 str. AP76	CP001091	2.35	2142	41.2	STHH^b
Actinobacillus ureae ATCC 25976^a	AEVG0	2.30	2475	—	BCM^g
Actinobacillus minor 202^a	ACFT0	2.13	2050	39.3	McGill University
Actinobacillus minor NM305^a	ACQL0	2.43	2411	39.3	McGill University
Actinobacillus succinogenes 130Z	CP000746	2.32	2079	44.9	Joint Genome Institute
Aggregatibacter aphrophilus NJ8700	CP001607	2.31	2219	42.2	[19, 42]
Aggregatibacter actinomycetemcomitans D11S-1	CP001733	2.20	2280	44.3	[43]
Aggregatibacter actinomycetemcomitans D7S-1	CP003496	2.31	2250	44.3	[44]
Aggregatibacter segnis ATCC 33393^a	AEPS0	1.99	1956	—	BCM^g
Gallibacterium anatis UMN179	CP002667	2.69	2500	39.9	[45]
Haemophilus aegyptius ATCC 11116^a	AFBC0	1.92	2020	—	BCM^g
Haemophilus ducreyi 35000HP	AE017143	1.70	1717	38.2	Ohio State University
Haemophilus haemolyticus M21621^a	AFQQ0	2.09	1894	—	[46]
Haemophilus influenzae 10810	FQ312006	1.98	1903	38.1	WTSI^h
Haemophilus influenzae F3031	FQ670178	1.99	1770	38.2	[47]
Haemophilus influenzae F3047	FQ670204	2.01	1786	38.2	[47]
Haemophilus influenzae 22.1-21^a	AAZD0	1.89	2224	38.0	[48]
Haemophilus influenzae 3655	AAZF0	1.88	1929	38.0	[48]
Haemophilus influenzae 6P18H1^a	ABWW0	1.91	1893	38.2	CGS, ASRI^e
Haemophilus influenzae 7P49H1^a	ABWV0	1.83	1752	37.9	CGS, ASRI^e
Haemophilus influenzae NT127^a	ACSL0	1.87	1809	38.0	BIGSP^c
Haemophilus influenzae PittAA^a	AAZG0	1.88	1981	38.1	[48]
Haemophilus influenzae PittII^a	AAZI0	1.95	2028	38.0	[48]
Haemophilus influenzae PittHH^a	AAZH0	1.84	1977	38.0	[48]
Haemophilus influenzae R3021^a	AAZJ0	1.88	2307	37.9	[48]
Haemophilus influenzae RdAW^a	ACSM0	1.80	1718	38.0	BIGSP^c
Haemophilus influenzae 86-028NP	CP000057	1.91	1792	38.2	[49]
Haemophilus influenzae PittEE	CP000671	1.81	1613	38.0	[48]
Haemophilus influenzae PittGG	CP000672	1.89	1661	38.0	[48]
Haemophilus influenzae Rd KW20	L42023	1.83	1657	38.2	[34]
Haemophilus influenzae R2846	CP002276	1.82	1636	38.0	UW-SBRI^d
Haemophilus influenzae R2866	CP002277	1.93	1795	38.1	UW-SBRI^d
Haemophilus parainfluenzae ATCC 33392^a	AEWU0	2.11	2010	—	BCM^g
Haemophilus parainfluenzae T3T1	FQ312002	2.09	1975	39.6	WTSI^h
Haemophilus parasuis 29755^a	ABKM0	2.22	2244	39.8	Iowa State University
Haemophilus parasuis SH0165	CP001321	2.27	2021	40.0	[50]
Haemophilus pittmaniae HK 85^a	AFUV0	2.18	2390	—	J. Craig Venter Institute
Haemophilus sputorum CCUG13788^a	AFNK0	2.14	2073	—	Aarhus University Hospital
Haemophilus parahaemolyticus HK385^a	AJSW0	1.81	1764	—	J. Craig Venter Institute
Haemophilus paraphrohaemolyticus HK411^a	AJMU0	2.02	2025	—	J. Craig Venter Institute
Haemophilus sp. oral taxon 851 str.F0397^a	AGRK0	1.84	1809	—	GCG-WU^f
Histophilus somni 2336	CP000947	2.26	1980	37.4	Joint Genome Institute
Histophilus somni 129PT	CP000436	2.01	1798	37.2	[51]
Mannheimia succiniciproducens MBEL55E	AE016827	2.31	2370	42.5	[52]
Mannheimia haemolytica PHL213^a	AASA0	2.57	2695	41.1	[53]
Pasteurella multocida subsp. multocida str. Pm70	AE004439	2.26	2012	40.4	[54]
Pasteurella dagmatis ATCC 43325^a	ACZR0	2.25	2053	37.4	BCM^g

The genomes of these species/strains are currently under scaffolds/contigs status.
^bStiftung Tieraerztliche Hochschule Hannover (STHH).
^cThe Broad Institute Genome Sequencing Platform (BIGSP).
^dUniversity of Washington; Seattle Biomedical Research Institute (UW-SBRI).
^eCenter for Genomic Sciences, Allegheny-Singer Research Institute (CGS, ASRI).
^fGenome Sequencing Center (GSC) at Washington University (WashU) School of Medicine.
^gBaylor College of Medicine (BCM).
^hWellcome Trust Sanger Institute (WTSI).