(a)
(b)
(c)
Figure 3: Comparison of PPI prediction accuracy in the Phyloprof category. (a) PPI prediction based on classifiers related to SC. (b) PPI prediction based on classifiers related to cross species. (c) PPI prediction based on classifiers related to all species. “Average” represents the mean AUC of all the classifiers in each category. “Highest” represents the classifier with highest AUC among all the classifiers in each category. Error bars show standard deviation. “” indicates that AUC of PPCM was significantly ( value < 0.05; -test) higher than that of the most accurate classifier in each category.