Transcriptome Analysis of Bovine Ovarian Follicles at Predeviation and Onset of Deviation Stages of a Follicular Wave
Table 3
List of upregulated genes in ODF1 versus PDF1 and their functions.
Gene symbol
GenBank number
PDF1 RPKM
ODF1 RPKM
Fold change
FDR corrected value
Gene product functions
GAPDH
XM_001252511.3
1.91
59.65
31.91
9.83 × 10−11
Microtubule and NAD binding
BOLA-N
NM_001105651.1
14.28
174.88
12.50
Unknown
PPP1R14A
NM_001193070.1
6.06
65.75
11.08
8.98 × 10−10
Smooth muscle contraction
LOC505676
NM_001193296.1
14.04
111.19
8.09
Unknown
LOC100337308
XM_002684003.1
3.72
23.27
6.39
4.40 × 10−2
Unknown
MT1A
NM_001040492.2
26.50
150.75
5.81
Bind heavy metals
LOC100125916
NM_001105487.1
14.80
83.88
5.78
1.51 × 10−9
Unknown
TNFAIP6
NM_001007813.1
11.17
46.61
4.26
1.06 × 10−3
Cell-cell and cell-matrix interactions
BEX2
NM_001077034.1
93.97
345.00
3.75
Mitochondrial apoptosis
GPR85
NM_001075150.2
10.06
35.54
3.61
4.05 × 10−2
G-protein coupled receptor
PPM1K
NM_001046474.1
34.75
108.32
3.18
2.52 × 10−7
Cellular survival and development
CYP19A1
NM_174305.1
656.88
1944.89
3.02
Estrogen biosynthesis
MT1E
NM_001114857.1
54.11
152.16
2.87
2.61 × 10−9
Bind heavy metals
ETNK2
XM_002693881.1
22.35
61.96
2.83
4.65 × 10−3
Ethanolamine phosphorylation
CHST11
NM_001192668.1
57.39
154.72
2.75
6.77 × 10−9
Biosynthesis chondroitin sulfate
MT2A
NM_001075140.1
49.37
130.49
2.70
4.16 × 10−7
Bind heavy metals
PRSS23
NM_001080306.1
58.01
151.79
2.67
2.74 × 10−8
Follicular atresia
TXNIP
NM_001101875.2
98.64
231.47
2.40
6.64 × 10−11
Oxidative stress mediator
NPR3
NM_174127.2
47.55
106.35
2.28
5.93 × 10−4
Natriuretic peptide hormone receptor
GREB1
NM_001205631.1
35.17
78.20
2.27
1.30 × 10−2
Estrogen-stimulated cell proliferation
EIF4EBP1
NM_001077893.1
138.11
294.07
2.17
1.30 × 10−11
Mediates protein translation regulation
PIK3R1
NM_174575.1
113.42
210.95
1.90
1.21 × 10−5
Insulin actions metabolic
LRP8
NM_001097565.1
1061.54
1897.64
1.82
Sperm maturation
SCD5
NM_001076945.1
124.08
210.97
1.74
4.25 × 10−4
Energy metabolism
ENO1
NM_174049.2
1005.45
1707.61
1.73
Tumor suppressor
LDHA
NM_174099.2
221.85
366.73
1.69
3.41 × 10−7
Affiliated with lncrna
SERPINE2
NM_174669.2
6816.85
11075.44
1.66
Serine protease inhibitor
INHBA
NM_174363.2
5824.46
9440.24
1.65
Regulate gonadal stromal cell proliferation
TMEM176B
NM_001099145.1
106.45
170.39
1.63
2.16 × 10−2
Dendritic cells maturation
OAT
NM_001034240.1
395.42
630.73
1.63
1.71 × 10−11
Ornithine aminotransferase
CYP11A1
NM_176644.2
908.97
1425.87
1.60
Cholesterol to pregnenolone
OBSL1
XM_002685586.1
221.33
338.40
1.56
1.16 × 10−4
Regulate ubiquitin ligase complex
ARFGAP3
NM_001075974.1
273.92
418.22
1.56
5.26 × 10−6
Gtpase-activating protein
ITGB5
NM_174679.2
153.24
233.56
1.56
7.68 × 10−3
Fibronectin receptor
INHA
NM_174094.3
6341.61
9658.83
1.55
Gonadal hormone secretion
OPTN
NM_001034602.1
160.13
243.40
1.55
5.92 × 10−3
Affect cell death
PTGR1
NM_001035281.1
200.07
301.66
1.54
9.40 × 10−4
Inactivation of the chemotactic factor
STBD1
XM_002688357.1
143.24
215.66
1.54
2.15 × 10−2
Bind to carbohydrates
LOC532189
XR_083049.1
340.18
510.18
1.53
5.69 × 10−7
Carboxypeptidase
TMEM20
NM_001076470.1
191.10
286.48
1.53
2.10 × 10−3
Solute carrier
ECE1
NM_181009.2
461.24
691.33
1.53
8.98 × 10−10
Converts big endothelin-1 to endothelin-1
GNG10
NM_001114512.1
617.73
918.26
1.52
7.59 × 10−13
Signal transducer
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