Research Article

miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction

Figure 6

KEGG annotations of differentially expressed cardiac-specific miRNAs from left ventricular tissue samples of MI rats (model group) and non-MI rats (control group). The miRNA versus pathway heatmap was created directly from the DIANA-miRPath v3.0 online tool. The heatmap depicts the level of enrichment in pathways of 3 differentially expressed cardiac-specific miRNAs. There were 14 predicted pathways integrating with 3 differentially expressed cardiac-specific miRNAs in the heatmap. The pathway clustering tree is shown on the top, and the legend on the bottom indicates the pathway represented in the corresponding column. The miRNA clustering tree is shown on the left, and the legend on the right indicates the miRNA represented in the corresponding row. The color scale shown on the upper left corner illustrates the predicted correlation degree of pathways with the miRNAs (shown as log value).