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International Journal of Genomics
Volume 2017, Article ID 2354564, 13 pages
https://doi.org/10.1155/2017/2354564
Research Article

Characteristics and Validation Techniques for PCA-Based Gene-Expression Signatures

Department of Biostatistics and Bioinformatics, Division of Population Sciences, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

Correspondence should be addressed to Anders E. Berglund; gro.ttiffom@dnulgreb.sredna

Received 27 September 2016; Revised 15 December 2016; Accepted 4 January 2017; Published 6 February 2017

Academic Editor: Bethany Wolf

Copyright © 2017 Anders E. Berglund et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Andrew Dhawan, Alessandro Barberis, Wei-Chen Cheng, Enric Domingo, Catharine West, Tim Maughan, Jacob G. Scott, Adrian L. Harris, and Francesca M. Buffa. View at Publisher · View at Google Scholar
  • Zhihua Shao, Haiyun Wang, Xuejian Zhou, Baosen Guo, Xuehu Gao, Zengrong Xiao, Meng Liu, Jihong Sha, Chunlian Jiang, Yuping Luo, Zhixue Liu, and Siguang Li, “Spontaneous generation of a novel foetal human retinal pigment epithelium (RPE) cell line available for investigation on phagocytosis and morphogenesis,” Cell Proliferation, pp. e12386, 2017. View at Publisher · View at Google Scholar
  • Jennifer K. Melbourne, Cherise Rosen, Benjamin Feiner, Yanzhen Pang, and Rajiv P. Sharma, “The JAK-STAT1 transcriptional signature in peripheral immune cells reveals alterations related to illness duration and acuity in psychosis,” Brain, Behavior, and Immunity, 2018. View at Publisher · View at Google Scholar
  • Anders E. Berglund, Eric A. Klein, Stephen J. Freedland, Ashley E. Ross, John L. Cleveland, Jong Y. Park, Jasreman Dhillon, Kosj Yamoah, Shivanshu Awasthi, Elai Davicioni, Nicholas Erho, Edward M. Schaeffer, Bruce J. Trock, Robert B. Den, Robert J. Rounbehler, Travis Gerke, Chia-Ho Cheng, Mandeep Takhar, and Mohammed Alshalalfa, “Distinct transcriptional repertoire of the androgen receptor in ETS fusion-negative prostate cancer,” Prostate Cancer and Prostatic Diseases, 2018. View at Publisher · View at Google Scholar
  • Andrew Dhawan, Alessandro Barberis, Wei-Chen Cheng, Enric Domingo, Catharine West, Tim Maughan, Jacob G. Scott, Adrian L. Harris, and Francesca M. Buffa, “Guidelines for using sigQC for systematic evaluation of gene signatures,” Nature Protocols, 2019. View at Publisher · View at Google Scholar